CpG island and isochore detection
http://edamontology.org/operation_0430
Find CpG rich regions in a nucleotide sequence or isochores in genome sequences.
Synonyms: CpG island and isochores detection, CpG island and isochores rendering
Term info
Subsets
operations, edam
Created in
beta12orEarlier
comment
An isochore is long region (> 3 KB) of DNA with very uniform GC content, in contrast to the rest of the genome. Isochores tend tends to have more genes, higher local melting or denaturation temperatures, and different flexibility. Methods might calculate fractional GC content or variation of GC content, predict methylation status of CpG islands etc. This includes methods that visualise CpG rich regions in a nucleotide sequence, for example plot isochores in a genome sequence.