Protein folds and structural domains
http://edamontology.org/topic_0736
Protein tertiary structural domains and folds in a protein or polypeptide chain.
Synonyms: Protein domains, Protein membrane regions, Protein topological domains, Protein folds, Protein transmembrane regions, Protein structural domains, Intramembrane regions, Transmembrane regions
Term info
edam, topics
beta12orEarlier
This includes trans- or intra-membrane regions of a protein, typically describing physicochemical properties of the secondary structure elements. For example, the location and size of the membrane spanning segments and intervening loop regions, transmembrane region IN/OUT orientation relative to the membrane, plus the following data for each amino acid: A Z-coordinate (the distance to the membrane center), the free energy of membrane insertion (calculated in a sliding window over the sequence) and a reliability score. The z-coordinate implies information about re-entrant helices, interfacial helices, the tilt of a transmembrane helix and loop lengths., This includes topological domains such as cytoplasmic regions in a protein.
Protein_folds_and_structural_domains
true