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matrix metalloproteinase measurement

^ http://www.ebi.ac.uk/efo/EFO_0004744


Term info

definition

Is a quantification of matrix metalloproteinases, Collectively, they are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands (such as the FAS ligand), and chemokine/cytokine in/activation.[3] MMPs are also thought to play a major role on cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.

definition citation

http://en.wikipedia.org/wiki/Matrix_metalloproteinase

gwas trait

true

term editor

Helen Parkinson

Term relations

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