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CCL2 measurement

^ http://www.ebi.ac.uk/efo/EFO_0004749


Term info

definition

Is the quantification of Chemokine (C-C motif) ligand 2, involved in response to infection and inflammation. Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. CCL2 is reported to be associated with Alzheimer's disease e.g. http://www.ncbi.nlm.nih.gov/pubmed/22303443 and http://europepmc.org/abstract/MED/25340798

definition citation

http://en.wikipedia.org/wiki/CCL2, http://www.uniprot.org/uniprot/P13500

gwas trait

true

has exact synonym

MCP1 measurement, MCP-1 measurement, chemokine CCL2 levels, chemokine CCL2 level, monocyte chemoattractant protein-1 measurement, monocyte chemotactic protein-1 level, monocyte chemotactic protein-1 levels, monocyte chemotactic protein-1 measurement

term editor

Helen Parkinson