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interleukin 1 receptor antagonist measurement

^ http://www.ebi.ac.uk/efo/EFO_0004754

Term info

definition

Is a quantification of Interleukin 1 Receptor Antagonist (IL1-RA). Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure

definition citation

http://www.uniprot.org/uniprot/P18510

gwas trait

true

term editor

Helen Parkinson