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CD40 ligand measurement

^ http://www.ebi.ac.uk/efo/EFO_0004790

Term info

definition

Is a quantification of CD40 ligand, primarily expressed on activated CD4+ T lymphocytes. Protein function - mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.1 Publication Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

definition citation

http://en.wikipedia.org/wiki/CD40_ligand, http://www.uniprot.org/uniprot/P29965, D023201

gwas trait

true

has exact synonym

CD154 ligand measurement

term editor

Helen Parkinson

Term relations