tissue plasminogen activator measurement
http://www.ebi.ac.uk/efo/EFO_0004791
Term info
definition
Is a quantification of tissue plasminogen activator, an enzyme which converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Play a direct role in facilitating neuronal migration.
definition citation
http://europepmc.org/abstract/MED/24578379, http://www.uniprot.org/uniprot/P00750
gwas trait
true
term editor
Helen Parkinson