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alpha macroglobulin measurement

^ http://www.ebi.ac.uk/efo/EFO_0004815


Term info

definition

Is a quantification of alphamacroglobulins 1 and/or 2, glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters. Chronic kidney disease can result in the leakage of alphamacroglobulins into the blood.

definition citation

http://en.wikipedia.org/wiki/Alpha-macroglobulin

gwas trait

true

term editor

Helen Parkinson

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