asymmetrical dimethylarginine measurement
http://www.ebi.ac.uk/efo/EFO_0006522
Term info
definition
quantification of the amount of asymmetrical dimethylarginine in blood. Asymmetric dimethylarginine (ADMA) is an independent risk factor for coronary heart disease in patients with heart disease, type II diabetes or kidney disease. ADMA inhibits nitric oxide (NO) synthesis and is elevated in diseases related to endothelial dysfunction including hypertension, hyperlipidemia, and type-II diabetes mellitus. Elevation in ADMA and subsequent NO synthesis inhibition leads to vasoconstriction, reduced peripheral blood flow, and reduced cardiac output.
definition citation
https://en.wikipedia.org/wiki/Asymmetric_dimethylarginine
gwas trait
true
has exact synonym
ADMA measurement
term editor
Dani Welter