chromosome conformation capture assay
http://www.ebi.ac.uk/efo/EFO_0007688
Term info
definition
Chromosome conformation capture techniques were designed to analyse the 3-dimensional organisation and interaction of chromatin in a cell. This class of techniques always begin with cross-linking of chromatin, to preserve interactions with genomic loci. Next, DNA is fragmented. Traditional chromosome conformation capture techniques rely on a subsequent proximity ligation step, although ligation-free chromosome conformation assays have also been developed.
term editor
Sirarat Sarntivijai