Term info
definition
Quantification of the clotting tendency of blood plasma following the addition of tissue factor. Prothrombin time requires the presence of factors I, II, V, VII, and X. It measures the extrinsic pathway of coagulation and can be used in conjunction with the activated partial thromboplastin time (aPTT) which measures the intrinsic pathway. It is used as a screening test and can be affected by vitamin K deficiency, liver disease, warfarin therapy or intestinal problems.
gwas trait
true
has exact synonym
PT/INR measurement, International normalized ratio of prothrombin time measurement, ProTime INR measurement
term editor
Laura Harris