GAM
http://www.ebi.ac.uk/efo/EFO_0009987
Term info
definition
Genome architecture mapping (GAM) is an assay designed to analyze 3D chromatin structure without relying on digestion and ligation. The procedure involves cryosectioning samples in random orientation, and then single nuclear profiles are isolated by laser microdissection. Each nuclear profile then undergoes high-throughput sequencing, and subsequent analysis can generate a matrix of inferred proximity between genomic regions.
term editor
Dani Welter