carbonic anhydrase 2
http://www.ebi.ac.uk/efo/EFO_0010161
Term info
definition
Carbonic anhydrase II (gene name CA2), is one of sixteen forms of human alpha carbonic anhydrases. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule. Loss of carbonic anhydrase activity in bones impairs the ability of osteoclasts to promote bone resorption, leading to osteopetrosis.
has exact synonym
CA-II, Car2, CAII
term editor
Baron Koylass