pseudo-bulk aggregation of single-cell expression data
http://www.ebi.ac.uk/efo/EFO_0030053
A processed matrix generation method that involves combining single-cell expression values from multiple cells in the same biological sample. Aggregation is typically performed by summation of count data for cells of the same (inferred) type. The aggregated expression profiles can then be used in the same manner as bulk RNA-seq data, especially in differential expression analyses. [ http://orcid.org/0000-0002-3564-4813 http://www.ncbi.nlm.nih.gov/pubmed/28045081 ]
Term info
paola
A processed matrix generation method that involves combining single-cell expression values from multiple cells in the same biological sample. Aggregation is typically performed by summation of count data for cells of the same (inferred) type. The aggregated expression profiles can then be used in the same manner as bulk RNA-seq data, especially in differential expression analyses.
pseudo-bulk RNA-seq