mCT-seq
A method that can jointly capture cytosine DNA methylome (5mC) and transcriptome profiles from single cells/nuclei by partitioning RNA and DNA molecules through the incorporation of 5’-methyl-dCTP instead of dCTP during reverse transcription of RNA. [ http://orcid.org/0000-0002-1196-4871 https://www.biorxiv.org/content/10.1101/434845v1 ]
Term info
paola
2021-12-13T15:37:28Z
A method that can jointly capture cytosine DNA methylome (5mC) and transcriptome profiles from single cells/nuclei by partitioning RNA and DNA molecules through the incorporation of 5’-methyl-dCTP instead of dCTP during reverse transcription of RNA.
methylcytosine and transcriptome sequencing