JSON

monoblast

^ http://purl.obolibrary.org/obo/CL_0000040


A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. [ http://www.ncbi.nlm.nih.gov/pubmed/1104740 GOC:add http://en.wikipedia.org/wiki/Monoblast http://www.copewithcytokines.de ]

Term info

database cross reference
  • FMA:83553
  • CALOHA:TS-1195
comment

Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.

has related synonym

CFU-M, colony forming unit macrophage, colony forming unit monocyte, monocyte stem cell

prefLabel

Monoblast