endothelial cell

http://purl.obolibrary.org/obo/CL_0000115

An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. [ MESH:D042783 https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855 http://www.ncbi.nlm.nih.gov/pubmed/21275341 GOC:tfm http://en.wikipedia.org/wiki/Endothelial_cell ]

Synonyms: endotheliocyte

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Term history

Term info

database cross reference

BTO:0001176
CALOHA:TS-0278
FMA:66772

Subsets

human_reference_atlas

comment

From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]., The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart.

definition source

BTO:0001176, CL:0000115

has obo namespace

cell

imported from

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl

prefLabel

Endothelial cell

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

see also

URI: http://www.ebi.ac.uk/cellline#endothelial_cell, EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000467