T-helper 2 cell
http://purl.obolibrary.org/obo/CL_0000546
A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. [ http://purl.obolibrary.org/obo/go/references/0000031 GOC:add GOC:pam GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/20103781 http://www.ncbi.nlm.nih.gov/pubmed/19375293 http://www.ncbi.nlm.nih.gov/pubmed/22343568 ]
Synonyms: Th2 T cell, Th2 T-cell, T helper cells type 2, T(H)-2 cell, Th2 T-lymphocyte, Th2 T lymphocyte, Th2 cell, helper T cell type 2
Term info
- MESH:D018418
- BTO:0001679
- FMA:84385
human_reference_atlas
This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell.
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- CD4-positive helper T cell and has part some trans-acting T-cell-specific transcription factor GATA-3 and lacks_plasma_membrane_part some C-C chemokine receptor type 6 and lacks_plasma_membrane_part some C-X-C chemokine receptor type 3 and capable of some interleukin-4 production