megakaryocyte progenitor cell

http://purl.obolibrary.org/obo/CL_0000553

The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). [ http://openisbn.com/search.php?q=0721601464&isbn=1/ GOC:dsd GOC:tfm ]

Synonyms: MkP, megakaryoblast, Meg-CFC, megacaryocyte progenitor cell, colony-forming unit-megakaryocyte, CFU-Meg, megakaryocytic progenitor cell, megacaryoblast

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Term history

Term info

database cross reference

MESH:D055016
FMA:84235
CALOHA:TS-0610
BTO:0001164

Subsets

human_reference_atlas

comment

Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.

has related synonym

promegakaryocyte, promegacaryocyte

has obo namespace

cell

imported from

http://purl.obolibrary.org/obo/cl.owl

prefLabel

Megakaryoblast

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

Term relations

Equivalent to:

myeloid lineage restricted progenitor cell and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse) and capable of some endomitotic cell cycle and capable of some megakaryocyte differentiation
myeloid lineage restricted progenitor cell and capable of some endomitotic cell cycle and capable of some megakaryocyte differentiation and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)

Subclass of:

Related from:

develops_from

megakaryocyte