JSON

megakaryocyte

^ http://purl.obolibrary.org/obo/CL_0000556


A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. [ MESH:D008533 http://en.wikipedia.org/wiki/Megakaryocyte http://openisbn.com/search.php?q=0721601464&isbn=1/ ]

A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. [ http://openisbn.com/search.php?q=0721601464&isbn=1/ MESH:D008533 http://en.wikipedia.org/wiki/Megakaryocyte http://www.ncbi.nlm.nih.gov/pubmed/31043076 ]

Synonyms: megalocaryocyte, megacaryocyte, megalokaryocyte

Term info

database cross reference
  • BTO:0000843
  • CALOHA:TS-0611
  • FMA:83555
Subsets

human_reference_atlas

comment

Megakaryocytes are reportedly CD181-positive and CD182-positive.

imported from

http://purl.obolibrary.org/obo/cl.owl

prefLabel

Megakaryocyte

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606