mature B cell
http://purl.obolibrary.org/obo/CL_0000785
A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. [ GOC:dsd http://openisbn.com/search.php?q=0781735149&isbn=1/ GOC:add ]
Synonyms: mature B lymphocyte, mature B-lymphocyte, mature B-cell
Term info
Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.
Term relations
- B cell, CD19-positive and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and capable of some B cell activation and output of some mature B cell differentiation