CD4-positive, CD25-positive, alpha-beta regulatory T cell
http://purl.obolibrary.org/obo/CL_0000792
A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. [ http://www.ncbi.nlm.nih.gov/pubmed/22343568 GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/19464985 http://openisbn.com/search.php?q=0781735149&isbn=1/ GOC:add ]
Synonyms: CD4-positive, CD25-positive, alpha-beta regulatory T-cell, CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte, CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte
Term info
This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype.
suppressor T-cell, suppressor T-lymphocyte, Treg, suppressor T lymphocyte, suppressor T cell
Term relations
- CD4-positive, alpha-beta T cell and has plasma membrane part some interleukin-2 receptor subunit alpha and capable of some negative regulation of immune response and has low plasma membrane amount some interleukin-7 receptor subunit alpha