CD8-positive, alpha-beta cytotoxic T cell
http://purl.obolibrary.org/obo/CL_0000794
A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. [ GOC:tfm http://openisbn.com/search.php?q=0781735149&isbn=1/ http://purl.obolibrary.org/obo/go/references/0000031 GOC:pam GOC:add ]
Synonyms: CD8-positive, alpha-beta cytotoxic T lymphocyte, CD8-positive, alpha-beta cytotoxic T-lymphocyte, CD8-positive, alpha-beta cytotoxic T-cell
Term info
- CALOHA:TS-0190
- FMA:70573
human_reference_atlas
Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.
cytotoxic T cell, cytotoxic T lymphocyte, killer T-cell, killer T-lymphocyte, killer T lymphocyte, cytotoxic T-cell, cytotoxic T-lymphocyte, killer T cell
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- CD8-positive, alpha-beta T cell and has part some perforin-1 and has part some granzyme B and capable of some T cell mediated cytotoxicity and capable of some granzyme B localization to T cell secretory granule and output of some T cell differentiation
- CD8-positive, alpha-beta T cell
- capable of some T cell mediated cytotoxicity
- has part some granzyme B
- capable of some granzyme B localization to T cell secretory granule
- has part some perforin-1
- develops from some activated CD8-positive, alpha-beta T cell
- output of some T cell differentiation