immature single positive thymocyte
http://purl.obolibrary.org/obo/CL_0000805
A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. [ http://openisbn.com/search.php?q=0781735149&isbn=1/ GOC:tfm http://www.immgen.org/index_content.html http://purl.obolibrary.org/obo/go/references/0000031 GOC:add ]
Synonyms: immature single positive T lymphocyte, ISP, immature single positive T-lymphocyte, immature single positive T cell, T.ISP.th
Term info
Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages.
Term relations
- thymocyte and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha and has plasma membrane part some pre-T cell receptor complex and has plasma membrane part some T cell receptor co-receptor CD8 and has high plasma membrane amount some signal transducer CD24
- thymocyte
- protein-containing material entity
- has plasma membrane part some T cell receptor co-receptor CD8
- develops from some DN4 thymocyte
- lacks_plasma_membrane_part some CD44 molecule
- has high plasma membrane amount some signal transducer CD24
- lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha
- lacks_plasma_membrane_part some CD4 molecule
- has plasma membrane part some pre-T cell receptor complex