non-classical monocyte
http://purl.obolibrary.org/obo/CL_0000875
A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. [ http://www.ncbi.nlm.nih.gov/pubmed/20870168 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/16322748 http://www.ncbi.nlm.nih.gov/pubmed/20628149 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/18303997 ]
Synonyms: patrolling monocyte, resident monocyte
Term info
human_reference_atlas
Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-.
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- monocyte and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and bearer of some decreased size and capable of some lymphocyte costimulation and output of some monocyte differentiation and has high plasma membrane amount some CX3C chemokine receptor 1
- protein-containing material entity
- monocyte
- has high plasma membrane amount some CX3C chemokine receptor 1
- bearer of some decreased size
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some CD3 epsilon
- capable of some lymphocyte costimulation
- output of some monocyte differentiation
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- develops from some intermediate monocyte