Tc2 cell
http://purl.obolibrary.org/obo/CL_0000918
A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. [ GOC:add GOC:tfm http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/9914231 GOC:pam ]
Synonyms: Tc2 T cell, Th2 CD8-positive T cell, CD8-positive Th2 cell, T-cytotoxic T cell type 2, Tc2 T-cell, Th2 non-TFH CD8-positive T cell, Tc2 T-lymphocyte, Tc2 T lymphocyte
Term info
- FMA:84794
- BTO:0004794
This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell' (see CL:0001052), but includes the additional necessary and sufficient conditions to allow classification as a Tc2 T cell.
Term relations
- CD8-positive, alpha-beta cytokine secreting effector T cell and has part some trans-acting T-cell-specific transcription factor GATA-3 and lacks_plasma_membrane_part some C-C chemokine receptor type 6 and lacks_plasma_membrane_part some C-X-C chemokine receptor type 3 and capable of some interleukin-4 production