T3 B cell
http://purl.obolibrary.org/obo/CL_0000960
A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). [ http://www.ncbi.nlm.nih.gov/pubmed/12810111 http://www.ncbi.nlm.nih.gov/pubmed/17174121 GOC:msz http://purl.obolibrary.org/obo/go/references/0000031 http://www.immgen.org/index_content.html GOC:tfm ]
Synonyms: An1 B cell, T3 B-lymphocyte, T3 B lymphocyte, T3 B-cell, transitional stage 3 B cell
Term info
Term relations
- transitional stage B cell and participates_in some B cell anergy and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some L-selectin and has plasma membrane part some complement receptor type 2 and has plasma membrane part some low affinity immunoglobulin epsilon Fc receptor
- transitional stage B cell
- participates_in some B cell anergy
- has plasma membrane part some L-selectin
- has plasma membrane part some IgD immunoglobulin complex
- has plasma membrane part some low affinity immunoglobulin epsilon Fc receptor
- has plasma membrane part some complement receptor type 2
- develops from some T2 B cell