long lived plasma cell
http://purl.obolibrary.org/obo/CL_0000974
A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. [ GOC:msz GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/16014527 http://openisbn.com/search.php?q=9780781765190&isbn=1/ http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Term relations
- plasma cell and lacks_plasma_membrane_part some immunoglobulin complex and lacks_plasma_membrane_part some MHC class II protein complex and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has high plasma membrane amount some C-X-C chemokine receptor type 4 and has high plasma membrane amount some syndecan-1 and has low plasma membrane amount some CD19 molecule
- plasma cell
- lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- has high plasma membrane amount some C-X-C chemokine receptor type 4
- has high plasma membrane amount some syndecan-1
- develops from some short lived plasma cell
- has low plasma membrane amount some CD19 molecule