CD8_alpha-negative CD11b-negative dendritic cell
CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. [ http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC2346585 http://purl.obolibrary.org/obo/go/references/0000031 GOC:amm http:www.immgen.org/index_content.html ]
Synonyms: DC.8-4-11b-, triple negative dendritic cell
Term info
These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000011)(PMID:19243617).
Term relations
- conventional dendritic cell and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and has plasma membrane part some lymphocyte antigen 75 and capable of some antigen processing and presentation of peptide antigen via MHC class I
- myeloid leukocyte
- conventional dendritic cell
- lacks_plasma_membrane_part some integrin alpha-M
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain
- has plasma membrane part some lymphocyte antigen 75
- capable of some antigen processing and presentation of peptide antigen via MHC class I
- develops from some pre-conventional dendritic cell
- lacks_plasma_membrane_part some CD4 molecule