common myeloid progenitor, CD34-positive
http://purl.obolibrary.org/obo/CL_0001059
A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. [ http://www.ncbi.nlm.nih.gov/pubmed/16551251 http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC2212039 http://www.ncbi.nlm.nih.gov/pubmed/10724173 http://openisbn.com/search.php?q=0878932437&isbn=1/ GOC:tfm GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/16647566 GOC:add ]
Synonyms: common myeloid precursor, CD34-positive
Term info
CMP are reportedly CD16-positive, CD32-positive, CD38-positive, CD45RA-negative, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.
colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte, CFU-GEMM, myeloid stem cell, multipotential myeloid stem cell, CFU-S, pluripotent stem cell (bone marrow)
Term relations
- common myeloid progenitor and has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and has part some endothelial transcription factor GATA-2 and has plasma membrane part some CD34 molecule and capable of some myeloid leukocyte differentiation and capable of some myeloid dendritic cell differentiation
- progenitor cell
- protein-containing material entity
- common myeloid progenitor
- capable of some myeloid dendritic cell differentiation
- has part some transcription factor PU.1
- has part some CCAAT/enhancer-binding protein alpha
- has part some erythroid transcription factor
- has part some endothelial transcription factor GATA-2
- has plasma membrane part some CD34 molecule