Tc17 cell
http://purl.obolibrary.org/obo/CL_0002128
A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg. [ http://www.ncbi.nlm.nih.gov/pubmed/22343568 GOC:dsd GOC:tfm GOC:add http://www.ncbi.nlm.nih.gov/pubmed/19201830 ]
Synonyms: Tc17 T cell, Tc17 CD8+ T cell, Tc17 T-cell, Th17 CD8-positive T cell, Tc17 T lymphocyte, CD8-positive Th17 cell, Tc17 T-lymphocyte, Th17 non-TFH CD8-positive T cell
Term info
This cell type is compatible with the HIPC Lyoplate markers for 'Tc17 CD8+ T cell', but its logical definition includes additional known characteristics of Tc17 T cells. Found in the CD27-positive, CD28-positive or CD27-negative, CD28-positive fractions with the phenotype CCR4-negative and CCR7-negative (this sentence not part of definition).
Term relations
- CD8-positive, alpha-beta cytokine secreting effector T cell and lacks_plasma_membrane_part some receptor-type tyrosine-protein phosphatase C isoform CD45RA and has plasma membrane part some C-C chemokine receptor type 6 and capable of some interleukin-17 production and has high plasma membrane amount some C-C chemokine receptor type 5
- CD8-positive, alpha-beta cytokine secreting effector T cell
- has plasma membrane part some C-C chemokine receptor type 6
- capable of some interleukin-17 production
- lacks_plasma_membrane_part some receptor-type tyrosine-protein phosphatase C isoform CD45RA
- has high plasma membrane amount some C-C chemokine receptor type 5