CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell
http://purl.obolibrary.org/obo/CL_4030038
A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. [ http://www.ncbi.nlm.nih.gov/pubmed/21281815 http://www.ncbi.nlm.nih.gov/pubmed/23124355 ]
Term info
After acute tubular injury, this cell type becomes more numerous. In healthy rat kidneys, this cell is not detectable, whereas after unilateral ureteral obstruction (renal injury), it may appear de novo, arguing against the notion that this cell type represents a pre-existing progenitor cell population. In at least one study, data indicate that this cell type represents transiently dedifferentiated tubular cells involved in regeneration.
2023-03-07T14:17:39Z
CD133+CD24+CD106- tubular cell, CD24+CD133+ tubular cell, CD24-positive tubular cell
Term relations
- epithelial cell of proximal tubule
- part of some proximal tubular epithelium
- expresses some prominin-1
- expresses some signal transducer CD24