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secondary crest myofibroblast

^ http://purl.obolibrary.org/obo/CL_4033016


A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. [ http://www.ncbi.nlm.nih.gov/pubmed/33624948 http://www.ncbi.nlm.nih.gov/pubmed/31331942 ]

Synonyms: secondary-crest myofibroblast

Term info

contributor

https://orcid.org/0000-0001-6677-8489, https://orcid.org/0000-0002-9185-3994

date

2023-03-16T09:17:47Z

has related synonym

alveolar myofibroblast, SCMFs, SCMF