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epithelial to mesenchymal transition

^ http://purl.obolibrary.org/obo/GO_0001837


A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [ GOC:dph http://www.ncbi.nlm.nih.gov/pubmed/14701881 ]

Synonyms: mesenchymal cell differentiation from epithelial cell, epithelial-mesenchymal transition, EMT