JSON

B-1 B cell homeostasis

^ http://purl.obolibrary.org/obo/GO_0001922


The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. [ http://openisbn.com/search.php?q=0781735149&isbn=1/ GOC:add ]

Synonyms: B-1 B lymphocyte homeostasis, B-1 B-lymphocyte homeostasis, B-1 B-cell homeostasis

Term info

comment

Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.

has obo namespace

biological_process

id

GO:0001922