germinal center B cell differentiation

http://purl.obolibrary.org/obo/GO_0002314

The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). [ GOC:jal http://openisbn.com/search.php?q=0781735149&isbn=1/ ]

Synonyms: germinal center B lymphocyte differentiation, germinal center B-lymphocyte differentiation, germinal center B-cell differentiation

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Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

has related synonym

germinal center B cell development

has obo namespace

biological_process

GO:0002314

Term relations

Equivalent to:

cell differentiation and results in acquisition of features of some germinal center B cell

Subclass of:

Related from:

output of

Bm5 B cell