protein tyrosine kinase activity

http://purl.obolibrary.org/obo/GO_0004713

Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [ http://www.rhea-db.org/reaction.xhtml?id=10596 ]

Synonyms: protein-tyrosine kinase activity

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Term history

Term info

database cross reference

Reactome:R-HSA-2404199 (IGF1,2:IGF1R autophosphorylates)
Reactome:R-HSA-354073 (Autophosphorylation of PTK2 at Y397)
Reactome:R-HSA-388831 (Phosphorylation of CD28)
Reactome:R-HSA-190388 (Autocatalytic phosphorylation of FGFR3c)
Reactome:R-HSA-5654428 (Activated FGFR4 phosphorylates SHC1)
Reactome:R-HSA-1839067 (Phosphorylation of BCR moiety of BCR-FGFR1)
Reactome:R-HSA-8847977 (FRK phosphorylates PTEN)
Reactome:R-HSA-2033490 (Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity)
Reactome:R-HSA-202216 (Phosphorylation of SLP-76)
Reactome:R-HSA-5683930 (WICH phosphorylates H2AFX on Y142)
Reactome:R-HSA-354124 (Phosphorylation of pPTK2 by SRC)
Reactome:R-HSA-373750 (SEMA4D interacts with Plexin-B1:ErbB2)
Reactome:R-HSA-9680248 (Phosphorylation of extracellular domain KIT mutants)
Reactome:R-HSA-2012082 (Autocatalytic phosphorylation of FGFR3 cysteine mutants)
Reactome:R-HSA-4420117 (VEGFR2 autophosphorylates)
Reactome:R-HSA-5686587 (ABL1 phosphorylates RAD52)
Reactome:R-HSA-8851933 (MET phosphorylates GAB1)
Reactome:R-HSA-190429 (Autocatalytic phosphorylation of FGFR1c)
RHEA:10596 (skos:exactMatch)
Reactome:R-HSA-9672173 (Autophosphorylation of PDGFRA extracellular domain dimers)
Reactome:R-HSA-5654545 (Ligand-independent phosphorylation of overexpressed FGFR1c)
Reactome:R-HSA-9673761 (Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB)
Reactome:R-HSA-2404193 (IGF1R phosphorylates SHC1)
Reactome:R-HSA-3928648 (SFKs phosphorylate NGEF)
Reactome:R-HSA-5621363 (SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2)
Reactome:R-HSA-8942607 (Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes)
Reactome:R-HSA-8848077 (PTK6 phosphorylates STAP2)
Reactome:R-HSA-5654407 (Activated FGFR2 phosphorylates SHC1)
Reactome:R-HSA-210872 (Trans-phosphorylation of Tie2)
Reactome:R-HSA-9664278 (Phosphorylation and activation of PLCG due to FCGR3A effect)
Reactome:R-HSA-445091 (Phosphorylation of Neurofascin)
Reactome:R-HSA-1839065 (Phosphorylation of cytosolic FGFR1 fusion dimers)
Reactome:R-HSA-5218812 (FYN phosphorylates PAK2)
Reactome:R-HSA-419646 (SEMA4D interacts with Plexin-B1:Met)
Reactome:R-HSA-5218828 (PTK2/SRC-1 phosphorylates BCAR1)
Reactome:R-HSA-1251922 (PLCG1 phosphorylation by p-EGFR:p-ERBB2)
Reactome:R-HSA-3928583 (FYN phosphorylates NMDAR2B)
Reactome:R-HSA-5654634 (Activated FGFR3 phosphorylates SHC1)
Reactome:R-HSA-909730 (Phosphorylation of INFAR1 by TYK2)
Reactome:R-HSA-912629 (CBL is tyrosine phosphorylated)
Reactome:R-HSA-1472121 (Phosphorylation of p-KIT on Y900 by Src kinases)
Reactome:R-HSA-3928604 (SFKs phosphorylate VAV2,3)
Reactome:R-HSA-1839110 (p-BCR-p-FGFR1 phosphorylates GAB2)
Reactome:R-HSA-5218640 (SRC-1 phosphorylates p-Y397-PTK2)
Reactome:R-HSA-9029151 (JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1)
Reactome:R-HSA-9666425 (p-6Y-SYK phosphorylates VAV1,2,3)
Reactome:R-HSA-8849042 (PTK6 phosphorylates KHDRBS3)
Reactome:R-HSA-432129 (FGR binds and phosphorylates LRP8)
Reactome:R-HSA-9006332 (JAK2 transphosphorylates and is activated in response to Erythropoietin)
Reactome:R-HSA-9698005 (FLT3 ITD mutants phosphorylate STAT5)
Reactome:R-HSA-2029989 (Autocatalytic phosphorylation of overexpressed FGFR2 variants)
Reactome:R-HSA-190427 (Autocatalytic phosphorylation of FGFR1b)
Reactome:R-HSA-5654151 (Activated FGFR4 phosphorylates PLCG1)
Reactome:R-HSA-9665704 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1)
Reactome:R-HSA-1433506 (Phosphorylation of APS)
Reactome:R-HSA-9664275 (Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers)
Reactome:R-HSA-5218642 (PTK2 autophosphorylates)
Reactome:R-HSA-9032854 (NTRK2 phosphorylates CDK5)
Reactome:R-HSA-5654408 (Activated FGFR3 phosphorylates FRS2)
Reactome:R-HSA-8849068 (PTK6 phosphorylates ARHGAP35)
Reactome:R-HSA-443817 (Phosphorylation of L1 by EPHB2)
Reactome:R-HSA-2130194 (ABL phosphorylates WAVEs)
Reactome:R-HSA-2454239 (Phosphorylation of SYK)
Reactome:R-HSA-8848975 (PTK6 phosphorylates KHDRBS1)
Reactome:R-HSA-9603420 (Activated NTRK3 promotes SRC autophosphorylation)
Reactome:R-HSA-8937807 (SRC phosphorylates RUNX3)
Reactome:R-HSA-8964252 (G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC)
Reactome:R-HSA-9604767 (FLT3LG dimer:FLT3 dimer autophosphorylates)
Reactome:R-HSA-2730862 (Autophosphorylation of LYN kinase)
Reactome:R-HSA-2671742 (JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin)
Reactome:R-HSA-377640 (Autophosphorylation of SRC)
Reactome:R-HSA-418163 (Activated Src activates ERK)
Reactome:R-HSA-9672175 (Autophosphorylation of PDGFR mutant dimers)
Reactome:R-HSA-389354 (Activation of Vav1)
Reactome:R-HSA-4420121 (SFKs phosphorylate PLCG1)
Reactome:R-HSA-391865 (Recruitment of FAK to NCAM1:Fyn in lipid rafts)
Reactome:R-HSA-5654147 (Activated FGFR2 phosphorylates PLCG1)
Reactome:R-HSA-374701 (Phosphorylation of DCC by Fyn)
Reactome:R-HSA-8853325 (Plasma membrane FGFR1 fusions autophosphorylate)
Reactome:R-HSA-5624486 (SFKs phosphorylates RAF1 on Y340,Y341)
Reactome:R-HSA-2730882 (Phosphorylation of PKC-theta)
Reactome:R-HSA-1839112 (Phosphorylation of STAT5 by cytosolic FGFR1 fusions)
Reactome:R-HSA-2038944 (Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity)
Reactome:R-HSA-1839098 (Activated FGFR1 mutants and fusions phosphorylate PLCG1)
Reactome:R-HSA-445084 (Phosphorylation of L1 by SRC)
Reactome:R-HSA-5218830 (SRC-1 phosphorylates PTK2-beta)
Reactome:R-HSA-8848726 (PTK6 phosphorylates BCAR1)
Reactome:R-HSA-445085 (Phosphorylation of VAV2)
Reactome:R-HSA-5357429 (AXL autophosphorylates on Y772 and Y814)
Reactome:R-HSA-1248655 (Trans-autophosphorylation of EGFRvIII mutant dimers)
Reactome:R-HSA-9706350 (FLT3 phosphorylates CBL)
Reactome:R-HSA-4093332 (p-EPHB phosphorylates SDC2)
Reactome:R-HSA-3928578 (EPH receptors autophosphorylate)
Reactome:R-HSA-399934 (Phosphorylation of Plexin-A)
Reactome:R-HSA-9625487 (PTK2 autophosphorylates downstream of EGFR)
Reactome:R-HSA-1433418 (Phosphorylation of JAK2)
Reactome:R-HSA-909726 (Phosphorylation of STAT1)
Reactome:R-HSA-9006323 (Phospho-JAK2 phosphorylates EPOR)
Reactome:R-HSA-1250315 (Trans-autophosphorylation of ERBB4 homodimers)
Reactome:R-HSA-5637795 (Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant)
Reactome:R-HSA-2012073 (Autocatalytic phosphorylation of FGFR3c P250R mutant)
Reactome:R-HSA-2424484 (Phosphorylation of BTK by p-SYK)
Reactome:R-HSA-9673756 (Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins)
Reactome:R-HSA-9027425 (LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2)
Reactome:R-HSA-8853313 (FGFR2 fusions autophosphorylate)
Reactome:R-HSA-3928594 (SFKs phosphorylate GIT1)
Reactome:R-HSA-9669890 (Constitutive phosphorylation of kinase domain KIT mutants)
Reactome:R-HSA-429441 (SYK activation by SRC)
Reactome:R-HSA-873924 (Phosphorylation of IFNGR1 by JAK kinases)
Reactome:R-HSA-2033485 (Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity)
Reactome:R-HSA-983707 (SYK autophosphorylates at the activated BCR)
Reactome:R-HSA-8876230 (InlB:MET dimer trans-autophophorylates)
Reactome:R-HSA-8849102 (SRMS phosphorylates PTK6)
Reactome:R-HSA-5654653 (Activated FGFR4 phosphorylates FRS3)
Reactome:R-HSA-983709 (LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B))
Reactome:R-HSA-2424486 (Phosphorylation and activation of VAV2/VAV3 by SYK)
Reactome:R-HSA-8937844 (SRC,YES1 phosphorylate YAP1)
Reactome:R-HSA-8876948 (SRC phosphorylates InlA-bound CDH1 and CTNNB1)
Reactome:R-HSA-202233 (Inactivation of Lck by Csk)
Reactome:R-HSA-9670412 (Phosphorylation of STATs downstream of KIT mutants)
Reactome:R-HSA-5655301 (Activated FGFR2 mutants phosphorylate PLCG1)
Reactome:R-HSA-191062 (Autocatalytic phosphorylation of Klotho-bound FGFR1c)
Reactome:R-HSA-6784006 (STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2)
Reactome:R-HSA-5655270 (Activated FGFR3 mutants phosphorylate FRS2)
Reactome:R-HSA-5655284 (Activated FGFR4 mutants phosphorylate FRS2)
Reactome:R-HSA-9012650 (JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2)
Reactome:R-HSA-8848873 (PTK6 phosphorylates ARAP1)
Reactome:R-HSA-2029984 (Autocatalytic phosphorylation of FGFR2 ligand-independent mutants)
Reactome:R-HSA-8848606 (PTK6 phosphorylates PXN)
Reactome:R-HSA-8937728 (SRC phosphorylates RUNX1)
Reactome:R-HSA-373747 (Phosphorylation of nephrin by FYN)
Reactome:R-HSA-873918 (Transphosphorylation of JAK1)
Reactome:R-HSA-9037040 (SRC,FYN phosphorylate NTRK2)
Reactome:R-HSA-1250348 (Phosphorylation of SHC1 by ERBB4 homodimers)
Reactome:R-HSA-5654582 (Activated FGFR1 phosphorylates SHC1)
Reactome:R-HSA-388833 (Phosphorylation of CTLA-4)
Reactome:R-HSA-9699578 (Active FLT3 phosphorylates CDKN1B)
Reactome:R-HSA-2424487 (Phosphorylation of PLC-gamma by p-BTK/p-SYK)
Reactome:R-HSA-1225960 (Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants)
Reactome:R-HSA-5654655 (Activated FGFR4 phosphorylates PPTN11)
Reactome:R-HSA-186786 (Autophosphorylation of PDGF beta receptors)
Reactome:R-HSA-2730843 (Phosphorylation of LAT by p-SYK)
Reactome:R-HSA-418859 (Phosphorylation of Unc5C)
Reactome:R-HSA-9034875 (NTRK3 phosphorylates SHC1)
Reactome:R-HSA-8857555 (EGFR phosphorylates GPNMB)
Reactome:R-HSA-2033486 (Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding)
Reactome:R-HSA-5654628 (Activated FGFR3 phosphorylates FRS3)
Reactome:R-HSA-8983872 (JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4)
Reactome:R-HSA-9034814 (NTRK3 phosphorylates PLCG1)
Reactome:R-HSA-5218806 (FYN autophosphorylates)
Reactome:R-HSA-210291 (Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src)
Reactome:R-HSA-2033488 (Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding)
Reactome:R-HSA-9698003 (FLT3 mutants phosphorylate GAB2)
Reactome:R-HSA-9664976 (Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1)
Reactome:R-HSA-9032426 (NTRK2 phosphorylates FRS3)
Reactome:R-HSA-8875817 (MET phosphorylates STAT3)
Reactome:R-HSA-9695834 (Constitutive phosphorylation of FLT3 mutants)
Reactome:R-HSA-9021609 (ESR-associated SRC autophosphorylates)
Reactome:R-HSA-5690702 (LYN phosphorylates CD22)
Reactome:R-HSA-4420206 (Phosphorylation of SRC-1)
Reactome:R-HSA-8855237 (FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1)
Reactome:R-HSA-5218851 (p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407)
Reactome:R-HSA-6784319 (JAK1,TYK2 phosphorylate JAK1,TYK2)
Reactome:R-HSA-202291 (Activation of Lck)
Reactome:R-HSA-112333 (SRC autophosphorylation is positively regulated by InlA-bound CDH1)
Reactome:R-HSA-2454208 (Phosphorylation of beta and gamma subunits by LYN)
Reactome:R-HSA-879925 (SHC1 bound to the common beta chain becomes tyrosine phosphorylated)
Reactome:R-HSA-177930 (GAB1 phosphorylation by EGFR kinase)
Reactome:R-HSA-399947 (Tyrosine phosphorylation of CRMPs by Fes)
Reactome:R-HSA-2395801 (Phosphorylation of LAT by p-SYK)
Reactome:R-HSA-9026579 (NTRK2 phosphorylates PLCG1)
Reactome:R-HSA-8848776 (PTK6 phosphorylates DOK1)
Reactome:R-HSA-5655278 (Activated FGFR1 mutants phosphorylate FRS2)
Reactome:R-HSA-9612085 (SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs)
Reactome:R-HSA-389083 (Autophosphorylation of PDGF alpha receptors)
Reactome:R-HSA-8874078 (PTK2 autophosphorylates)
Reactome:R-HSA-1470009 (Phosphorylation of STATs)
Reactome:R-HSA-5654578 (Activated FGFR1 phosphorylates FRS3)
Reactome:R-HSA-372693 (Phosphorylation of BCAR1 by SRC-PTK2 complex)
Reactome:R-HSA-5621355 (LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG)
Reactome:R-HSA-9706344 (FLT3 phosphorylates GRB10)
Reactome:R-HSA-177937 (Phosphorylation of EGFR by SRC kinase)
Reactome:R-HSA-69195 (Phosphorylation of Cyclin E:CDK2 complexes by WEE1)
Reactome:R-HSA-5621370 (SYK autophosphorylates)
Reactome:R-HSA-5654397 (Activated FGFR2 phosphorylates FRS2)
Reactome:R-HSA-1169421 (Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers)
Reactome:R-HSA-2730858 (Autophosphorylation of BTK/ITK)
Reactome:R-HSA-202174 (Activation of ZAP-70)
Reactome:R-HSA-2029453 (Phosphorylation of VAV)
Reactome:R-HSA-2396594 (Phosphorylation of SLP-76 by p-SYK)
Reactome:R-HSA-451942 (Within the IL-2R complex JAK3 phosphorylates JAK1)
Reactome:R-HSA-174164 (Phosphorylation of Cyclin A:Cdk2 at Tyr 15)
Reactome:R-HSA-8848818 (PTK6 phosphorylates CBL)
Reactome:R-HSA-202168 (Phosphorylation of ZAP-70 by Lck)
Reactome:R-HSA-170991 (SRC-1 autophosphorylates)
Reactome:R-HSA-177934 (EGFR autophosphorylation)
Reactome:R-HSA-9703438 (FLT3 fusions phosphorylate GAB2)
Reactome:R-HSA-1982066 (Ligand-independent phosphorylation of overexpressed FGFR1)
Reactome:R-HSA-8867041 (EGFR phosphorylates EPS15)
Reactome:R-HSA-5654605 (Activated FGFR2 phosphorylates FRS3)
Reactome:R-HSA-9606162 (Phosphorylated BTK phosphorylates PLCG2)
Reactome:R-HSA-2586555 (JAK2 Autophosphorylates in Response to Leptin)
Reactome:R-HSA-2730886 (Phosphorylation of SHC by SYK kinase)
Reactome:R-HSA-2730833 (Phosphorylation of TEC kinases by p-SYK)
Reactome:R-HSA-1671691 (PRLR-bound STAT5 is phosphorylated)
Reactome:R-HSA-879907 (Tyrosine kinases phosphorylate the receptor)
Reactome:R-HSA-5654222 (Activated FGFR3 phosphorylates PLCG1)
Reactome:R-HSA-2730888 (Phosphorylation of PLC-gamma)
Reactome:R-HSA-9703437 (FLT3 fusion dimers autophosphorylate)
Reactome:R-HSA-1433488 (Phosphorylation of SHP2 by SFKs)
Reactome:R-HSA-389762 (Phosphorylation of PD-1)
Reactome:R-HSA-1524186 (Phosphorylation of PLCgamma by PDGFR)
Reactome:R-HSA-391866 (Phosphorylation of FAK by Src kinase)
Reactome:R-HSA-9034714 (NTRK3 dimers trans-autophosphorylate)
Reactome:R-HSA-391871 (Autophosphorylation of NCAM1 bound Fyn)
Reactome:R-HSA-1295609 (SRC phosphorylates SPRY2 on Y55 and Y227)
Reactome:R-HSA-1250195 (SHC1 phosphorylation by ERBB2 heterodimers)
Reactome:R-HSA-5655243 (Activated FGFR3 mutants phosphorylate PLCG1)
Reactome:R-HSA-190408 (Autocatalytic phosphorylation of FGFR2b)
Reactome:R-HSA-2395412 (Phosphorylation of SYK)
Reactome:R-HSA-2029268 (Phosphorylation and activation of PLCG)
Reactome:R-HSA-170156 (Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes)
Reactome:R-HSA-3928580 (SFKs phosphorylate EFNBs)
Reactome:R-HSA-8876246 (InlB-activated MET phosphorylates CBL)
Reactome:R-HSA-8948143 (p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18)
Reactome:R-HSA-9026502 (NTF3-bound NTRK2 dimers trans-autophosphorylate)
Reactome:R-HSA-190385 (Autocatalytic phosphorylation of FGFR3b)
Reactome:R-HSA-9665411 (Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1)
Reactome:R-HSA-8857577 (LINC01139 facilitates PTK6 autophosphorylation)
Reactome:R-HSA-391156 (Phosphorylation of ITIM motif in SIRP alpha)
Reactome:R-HSA-5607750 (SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan)
Reactome:R-HSA-2671850 (JAK2 Phosphoryates STAT3 in Response to Leptin)
Reactome:R-HSA-9011241 (SRC phosphorylates ROBO3.1 in response to NTN1)
Reactome:R-HSA-9033284 (NTRK2 promotes TIAM1 phosphorylation)
Reactome:R-HSA-9018572 (EGFR phosphorylates NOTCH3)
Reactome:R-HSA-8849032 (PTK6 phosphorylates KHDRBS2)
Reactome:R-HSA-1168394 (STAT5 tyrosine phosphorylation)
Reactome:R-HSA-8874080 (SRC phosphorylates PTK2)
Reactome:R-HSA-8848124 (PTK6 phosphorylates STAT3)
Reactome:R-HSA-1295540 (IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5)
Reactome:R-HSA-9032532 (NTRK2-bound FYN autophosphorylates)
Reactome:R-HSA-8848005 (ERBB2 promotes PTK6 autophosphorylation)
Reactome:R-HSA-982807 (JAK2 phosphorylation of GHR)
Reactome:R-HSA-202307 (Change of PKC theta conformation)
Reactome:R-HSA-909729 (Activation of JAK kinases)
Reactome:R-HSA-2012087 (Autocatalytic phosphorylation of FGFR4 Y367C mutant)
Reactome:R-HSA-9665032 (Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1)
Reactome:R-HSA-9606163 (p-SYK and LYN phosphorylate BTK)
Reactome:R-HSA-5655341 (Activated FGFR4 mutants phosphorylate PLCG1)
Reactome:R-HSA-3928610 (PTK2 autophosphorylates at Y397)
Reactome:R-HSA-5655268 (Activated FGFR2 mutants phosphorylate FRS2)
Reactome:R-HSA-909732 (Phosphorylation of STAT2)
Reactome:R-HSA-2671829 (JAK2 Phosphorylates STAT5 in Response to Leptin)
Reactome:R-HSA-2428926 (IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4)
Reactome:R-HSA-389086 (Autophosphorylation of PDGF alpha/beta receptors)
Reactome:R-HSA-2395439 (Phosphorylation of DAP12)
Reactome:R-HSA-8853315 (Activated FGFR3 fusions phosphorylate FRS2)
Reactome:R-HSA-909718 (Formation of p-STAT1 homodimer)
Reactome:R-HSA-190413 (Autocatalytic phosphorylation of FGFR2c)
Reactome:R-HSA-1963581 (Trans-autophosphorylation of p-Y877-ERBB2 heterodimers)
Reactome:R-HSA-9665389 (Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate)
Reactome:R-HSA-1307963 (Autocatalytic phosphorylation of BetaKlotho-bound FGFR4)
Reactome:R-HSA-1888198 (FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3)
EC:2.7.10.2 (skos:narrowMatch)
Reactome:R-HSA-9606159 (BTK autophosphorylates)
Reactome:R-HSA-1225952 (Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants)
Reactome:R-HSA-2586553 (JAK2 Phosphorylates LEPR)
Reactome:R-HSA-9032601 (FYN-mediated phosphorylation of GRIN2B)
Reactome:R-HSA-428888 (Phosphorylation of ROBO1 by ABL kinase)
Reactome:R-HSA-2023460 (Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity)
Reactome:R-HSA-9664588 (ERBB2 KD mutants trans-autophosphorylate)
Reactome:R-HSA-9026510 (NTF4-bound NTRK2 dimers trans-autophosphorylate)
Reactome:R-HSA-8849463 (PTK6 phosphorylates SFPQ)
Reactome:R-HSA-205289 (Autophosphorylation of KIT)
Reactome:R-HSA-5218820 (Src kinases phosphorylate VAV)
Reactome:R-HSA-399946 (Recruitment and activation of Cdk5)
Reactome:R-HSA-445076 (Phosphorylation of Y1229 in L1)
Reactome:R-HSA-2029449 (Phosphorylation of SYK by Src kinases)
Reactome:R-HSA-452100 (SHC1 bound to IL2 receptor is phosphorylated)
Reactome:R-HSA-1247844 (Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants)
Reactome:R-HSA-8851890 (MET phosphorylates SHC1-2)
Reactome:R-HSA-2197698 (Src phosphorylate WASP,N-WASP)
Reactome:R-HSA-9027272 (EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2)
Reactome:R-HSA-9664261 (Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK)
Reactome:R-HSA-9665705 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1)
Reactome:R-HSA-5654149 (Activated FGFR1 phosphorylates PLCG1)
Reactome:R-HSA-9029155 (JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1)
Reactome:R-HSA-9613023 (NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates)
Reactome:R-HSA-983703 (p-6Y-SYK phosphorylates BLNK (SLP65))
Reactome:R-HSA-114600 (Fyn/Lyn-mediated phosphorylation of FcR1 gamma)
Reactome:R-HSA-1433454 (Phosphorylation of GAB2 by SFKs)
Reactome:R-HSA-170070 (Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes)
Reactome:R-HSA-1963582 (Trans-autophosphorylation of ERBB2 heterodimers)
Reactome:R-HSA-4420128 (SRC-1 phosphorylates SHB)
Reactome:R-HSA-5654587 (Activated FGFR1:p-FRS phosphorylates PPTN11)
Reactome:R-HSA-2029459 (Sequestering and phosphorylation Fc gamma receptors in the lipid rafts)
Reactome:R-HSA-183058 (Phosphorylation of CBL (EGFR:GRB2:CBL))
Reactome:R-HSA-191636 (Phosphorylation of Cx43 by c-src)
Reactome:R-HSA-873922 (Phosphorylation of STAT1 by JAK kinases)
Reactome:R-HSA-9024726 (LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1)
Reactome:R-HSA-1433542 (Phosphorylation and activation of VAV1)
Reactome:R-HSA-9027273 (JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1)
Reactome:R-HSA-212710 (EGFR activates PLC-gamma1 by phosphorylation)
Reactome:R-HSA-429449 (Syk activation leads to SLP-76 activation)
Reactome:R-HSA-1963586 (SRC family kinases phosphorylate ERBB2)
Reactome:R-HSA-380780 (Activation of Src)
Reactome:R-HSA-9670418 (Phosphorylation of JAK2 downstream of KIT mutants)
Reactome:R-HSA-8857925 (Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307)
Reactome:R-HSA-9634390 (ERBB2 homodimer phosphorylates SHC1)
Reactome:R-HSA-8857583 (LINC01139 promotes phosphorylation of HIF1A by PTK6)
Reactome:R-HSA-3215391 (PRMT5 is tyrosine phosphorylated by JAK2 V617F)
Reactome:R-HSA-202165 (Phosphorylation of ITAM motifs in CD3 complexes)
Reactome:R-HSA-190326 (Autocatalytic phosphorylation of FGFR4)
Reactome:R-HSA-6806974 (MET dimers autophosphorylate)
Reactome:R-HSA-5654607 (Activated FGFR2 phosphorylates PPTN11)
Reactome:R-HSA-2038387 (Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants)
Reactome:R-HSA-8874082 (MET phosphorylates PTK2)
Reactome:R-HSA-5218809 (PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118)
Reactome:R-HSA-5654418 (Activated FGFR4 phosphorylates FRS2)
Reactome:R-HSA-182969 (Phosphorylation of CBL (EGFR:CBL))
Reactome:R-HSA-879909 (Activation of STAT5a/b by JAK2)
Reactome:R-HSA-8964242 (G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC)
Reactome:R-HSA-2730884 (Phosphorylation of NTAL by p-SYK/Lyn)
Reactome:R-HSA-508282 (SYK is a substrate for JAK1)
Reactome:R-HSA-452122 (JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB)
Reactome:R-HSA-2201322 (TIRAP is phosphorylated by BTK)
Reactome:R-HSA-9026464 (BDNF-bound NTRK2 dimers trans-autophosphorylate)
Reactome:R-HSA-2730851 (Phosphorylation of SLP-76 by p-SYK)
Reactome:R-HSA-8848758 (PTK6 phosphorylates AKT1)
Reactome:R-HSA-452097 (Recruited STAT5 is phosphorylated)
Reactome:R-HSA-5637796 (Phosphorylation of SHC1 by p-5Y-EGFRvIII)
Reactome:R-HSA-2730860 (Phosphorylation of GAB2 by SYK/FYN)
Reactome:R-HSA-8956659 (ABL1 phosphorylates YAP1)
Reactome:R-HSA-5654631 (Activated FGFR3 phosphorylates PPTN11)
Reactome:R-HSA-873919 (Phosphorylation of JAK2)
Reactome:R-HSA-2023455 (Autocatalytic phosphorylation of FGFR1c P252X mutant dimers)
Reactome:R-HSA-5607745 (1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG)
Reactome:R-HSA-418872 (Phosphorylation of FADK1)
Reactome:R-HSA-9612996 (NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates)
Reactome:R-HSA-8853309 (Autocatalytic phosphorylation of FGFR3 fusions)
Reactome:R-HSA-68954 (Mcm2-7 is phosphorylated by DDK)
Reactome:R-HSA-5654575 (Activated FGFR1 phosphorylates FRS2)
Reactome:R-HSA-3928627 (EPHB phosphorylates TIAM1)
Reactome:R-HSA-202248 (Phosphorylation of PLC-gamma1)
Reactome:R-HSA-434836 (Syk/Lck phosphorylate LAT)
Reactome:R-HSA-202245 (Phosphorylation of TBSMs in LAT)
Reactome:R-HSA-9669911 (Phosphorylation of juxtamembrane domain KIT mutants)
Reactome:R-HSA-8875451 (MET phosphorylates CBL)
Reactome:R-HSA-1248694 (Trans-autophosphorylation of ERBB2 homodimer)
Reactome:R-HSA-6790087 (HVEM induses BTLA phosphorylation)
Reactome:R-HSA-9028728 (NTRK2 phosphorylates FRS2)
Reactome:R-HSA-171011 (Binding and activation of MAP Kinase)
Reactome:R-HSA-9026890 (NTRK2 phosphorylates SHC1)
Reactome:R-HSA-9665709 (ERBB2 TMD/JMD heterodimers trans-autophosphorylate)
Reactome:R-HSA-8848436 (PTK6 phosphorylates CDKN1B)