G protein-coupled receptor activity
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [ http://www.iuphar-db.org http://en.wikipedia.org/wiki/GPCR GOC:bf ]
Synonyms: GPCR activity, G-protein coupled receptor activity, receptor activity, G-protein coupled, G-protein linked receptor activity, G protein coupled receptor activity, ligand-dependent GPCR activity, G protein linked receptor activity
Term info
- Reactome:R-HSA-114552 (G12/13 activation by PAR)
- Reactome:R-HSA-114558 (Gq activation by PAR)
- Reactome:R-HSA-167408 (The high affinity receptor complex binds to G-protein)
- Wikipedia:GPCR
goslim_chembl
GO:0016526, GO:0001622, GO:0001623, GO:0001624, GO:0001625
Epstein-Barr Virus-induced receptor activity, EBV-induced receptor, super conserved receptor expressed in brain receptor activity, SREB receptor, RDC1 receptor activity, Mas proto-oncogene receptor activity, orphan GPCR activity, orphan G protein coupled receptor activity, orphan G-protein coupled receptor activity, G-protein coupled receptor activity, unknown ligand
molecular_function
GO:0004930