G protein-coupled receptor activity

http://purl.obolibrary.org/obo/GO_0004930

Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [ http://www.iuphar-db.org http://en.wikipedia.org/wiki/GPCR GOC:bf ]

Synonyms: GPCR activity, G-protein coupled receptor activity, receptor activity, G-protein coupled, G-protein linked receptor activity, G protein coupled receptor activity, ligand-dependent GPCR activity, G protein linked receptor activity

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Term history

Term info

database cross reference

Wikipedia:GPCR
Reactome:R-HSA-114552 (G12/13 activation by PAR)
Reactome:R-HSA-167408 (The high affinity receptor complex binds to G-protein)
Reactome:R-HSA-114558 (Gq activation by PAR)

Subsets

goslim_chembl

has alternative id

GO:0016526, GO:0001622, GO:0001623, GO:0001624, GO:0001625

has narrow synonym

Epstein-Barr Virus-induced receptor activity, EBV-induced receptor, super conserved receptor expressed in brain receptor activity, SREB receptor, RDC1 receptor activity, Mas proto-oncogene receptor activity, orphan GPCR activity, orphan G protein coupled receptor activity, orphan G-protein coupled receptor activity, G-protein coupled receptor activity, unknown ligand

has obo namespace

molecular_function

GO:0004930

Term relations

Subclass of:

Related from:

starts with

G protein-coupled receptor signaling pathway

capable of

G-protein coupled receptor