ubiquitin-like protein peptidase activity

http://purl.obolibrary.org/obo/GO_0019783

An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins. [ http://www.ncbi.nlm.nih.gov/pubmed/19489724 ]

Synonyms: ubiquitin-like protein-specific protease activity, small conjugating protein-specific isopeptidase activity, ubiquitinyl-like hydrolase activity, ubiquitin-like hydrolase activity, ubiquitin-like protein-specific isopeptidase activity, small conjugating protein-specific protease activity

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Term history

Term info

comment

While ubiquitin-like proteins can be rarely linked to substrates via bonds other than isopeptide bonds, all known ubiquitin-like peptidases cleave the isopeptide bond.

has alternative id

GO:0140491, GO:1904455, GO:1904454, GO:0070138

has narrow synonym

ubiquitin-like specific protease activity, ubiquitin-specific protease activity involved in positive regulation of ERAD pathway, ubiquitin-like-protein-specific protease activity, ubiquitin-specific protease activity involved in negative regulation of ERAD pathway

has obo namespace

molecular_function

GO:0019783

term tracker item

https://github.com/geneontology/go-ontology/issues/17398

Term relations

Subclass of:

peptidase activity