CD19 molecule
http://purl.obolibrary.org/obo/PR_000001002
A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. [ http://www.ncbi.nlm.nih.gov/pubmed/15778510 ]
Synonyms: CD19, T-cell surface antigen Leu-12, differentiation antigen CD19, B-lymphocyte surface antigen B4
Term info
- PIRSF:PIRSF016630
- IUPHARobj:2764
Category=gene. Requested by=CL.
protein
PR:000001002
http://purl.obolibrary.org/obo/cl.owl
Term relations
- early pro-B cell
- pre-conventional dendritic cell
- granulocyte
- granulocyte
- hematopoietic stem cell
- hematopoietic stem cell
- natural helper lymphocyte
- intermediate monocyte
- intermediate monocyte
- hematopoietic oligopotent progenitor cell, lineage-negative
- hematopoietic oligopotent progenitor cell, lineage-negative
- innate lymphoid cell
- erythroid progenitor cell, mammalian
- erythroid progenitor cell, mammalian
- CD14-positive monocyte
- CD14-positive monocyte
- common dendritic progenitor
- common dendritic progenitor
- dendritic cell
- dendritic cell
- non-classical monocyte
- classical monocyte
- classical monocyte
- hematopoietic multipotent progenitor cell
- hematopoietic multipotent progenitor cell
- mast cell progenitor
- erythroblast
- erythroblast
- eosinophil progenitor cell
- basophil progenitor cell
- reticulocyte
- reticulocyte
- megakaryocyte progenitor cell
- megakaryocyte progenitor cell
- proerythroblast
- proerythroblast