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integrin alpha-M

^ http://purl.obolibrary.org/obo/PR_000001012


An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. [ http://www.uniprot.org/uniprot/P11215 ]

Synonyms: ITGAM, cell surface glycoprotein MAC-1 subunit alpha, CD11 antigen-like family member B, CD11b, CR-3 alpha chain, leukocyte adhesion receptor MO1, neutrophil adherence receptor

Term info

database cross reference
  • IUPHARobj:2452
comment

Category=gene. Requested by=CL.

has related synonym

CR3A, CD11B

id

PR:000001012

imported from

http://purl.obolibrary.org/obo/cl.owl

Term relations

Related from:
lacks_plasma_membrane_part