integrin alpha-M
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. [ http://www.uniprot.org/uniprot/P11215 ]
Synonyms: ITGAM, cell surface glycoprotein MAC-1 subunit alpha, CD11 antigen-like family member B, CD11b, CR-3 alpha chain, leukocyte adhesion receptor MO1, neutrophil adherence receptor
Term info
- IUPHARobj:2452
Category=gene. Requested by=CL.
CR3A, CD11B
protein
PR:000001012
http://purl.obolibrary.org/obo/cl.owl
Term relations
- Kupffer cell
- alveolar macrophage
- lymph node macrophage
- splenic red pulp macrophage
- CD27-low, CD11b-low immature natural killer cell, mouse
- CD27-high, CD11b-low natural killer cell, mouse
- CD103-positive, langerin-positive lymph node dendritic cell
- liver CD103-positive dendritic cell
- CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell
- CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell
- peritoneal macrophage
- CD27-high, CD11b-high natural killer cell, mouse
- CD27-low, CD11b-high natural killer cell, mouse
- lymphoid MHC-II-negative classical monocyte
- lymphoid MHC-II-negative non-classical monocyte
- liver CD103-negative dendritic cell
- CD103-negative, langerin-positive lymph node dendritic cell
- group 2 innate lymphoid cell, mouse
- pre-conventional dendritic cell
- hematopoietic stem cell
- hematopoietic stem cell
- natural helper lymphocyte
- thymic plasmacytoid dendritic cell
- thymic conventional dendritic cell
- thymic conventional dendritic cell
- CD11c-low plasmacytoid dendritic cell
- CD8_alpha-negative CD11b-negative dendritic cell
- proerythroblast
- proerythroblast
- megakaryocyte progenitor cell
- megakaryocyte progenitor cell
- reticulocyte
- reticulocyte
- basophil progenitor cell
- eosinophil progenitor cell
- erythroblast
- erythroblast
- mast cell progenitor
- hematopoietic multipotent progenitor cell
- hematopoietic multipotent progenitor cell
- promyelocyte
- splenic marginal zone macrophage
- CD8_alpha-positive CD11b-negative dendritic cell
- common dendritic progenitor
- common dendritic progenitor
- erythroid progenitor cell, mammalian
- erythroid progenitor cell, mammalian
- hematopoietic oligopotent progenitor cell, lineage-negative
- hematopoietic oligopotent progenitor cell, lineage-negative