JSON

atrioventricular canal

^ http://purl.obolibrary.org/obo/UBERON_0002087

The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP]. [ http://en.wikipedia.org/wiki/Atrioventricular_canal ZFA:0001315 https://github.com/obophenotype/uberon/issues/38 ]

Synonyms: AV canal, atrio-ventricular canal, atrial canal, AVC

Term info

database cross reference
Subsets

uberon_slim, pheno_slim, vertebrate_core

UBPROP 0000001

The canal connecting the primitive atrium and ventricle in fishes and amniotes embryo. [TFD][VHOG]

UBPROP 0000003

The heart is the first organ to form and function in a vertebrate. (...) Septation of the AV canal is initiated with the formation of inferior and superior endocardial cushions in response to signaling from the overlying myocardium. (...) Analysis of zebrafish mutants with cardiovascular defects uncovered a previously unexpected level of conservation between zebrafish and human cardiovascular physiology.[uncertain][VHOG]

UBPROP 0000009

In the embryo, the atrioventricular canal delays the impulse from atrium to ventricle[PMID:22984480]

UBPROP 0000011

The right side of the AVC becomes the tricuspid valve whereas the left side of the AVC will become the bicuspid valve

UBPROP 0000012

this is a lumen in EHDAA2

contributor

https://github.com/cmungall, https://github.com/mellybelly, https://github.com/rfoulger

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/d8/Gray464.png

has related synonym

canalis atrioventricularis, ependymal canal

id

UBERON:0002087

prefLabel

Atrioventricular canal