JSON

cartilage tissue

^ http://purl.obolibrary.org/obo/UBERON_0002418

Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. [ http://dx.plos.org/10.1371/journal.pone.0051070 https://sourceforge.net/p/obo/vertebrate-skeletal-anatomy-vsao-term-requests/5 http://purl.obolibrary.org/obo/go/references/0000034 https://github.com/obophenotype/uberon/issues/37 PSPUB:0000170 VSAO:0000040 ]

Synonyms: cartilage tissue, chondrogenic tissue, cartilaginous tissue

Term info

database cross reference
  • EMAPA:32730
  • TAO:0001501
  • EHDAA2:0003087
  • MA:0000104
  • galen:Cartilage
  • NCIT:C12373
  • NCIT:C32268
  • MIAA:0000189
  • VHOG:0001207
  • GAID:99
  • EFO:0000949
  • UMLS:C0007301 (ncithesaurus:Cartilage)
  • EV:0100141
  • SCTID:309312004
  • VSAO:0000040
  • BTO:0000206
  • ZFA:0005622
  • MESH:D002356
  • XAO:0000170
  • AEO:0000087
  • FMA:37377
  • AAO:0000060
  • MAT:0000189
  • Wikipedia:Cartilage
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

UBPROP 0000001

Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO], A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO], Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]

UBPROP 0000002

relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]

UBPROP 0000003

Phylogenetic analysis suggests that cartilage arose independently in cnidarians, hemichordates, vertebrates, arthropods, annelids, brachiopods, and molluscs - or a common ancestor of brachiopods and molluscs (...). Analyses of cartilage as a tissue and of the development of invertebrate cartilages are consistent with homology between invertebrate and vertebrate cartilage. From the discussion above, it will be clear that understanding genetic changes underlying cartilage evolution is key to determining whether the multiple origins of cartilage represent parallel evolution.[well established][VHOG]

comment

Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W]

contributor

https://github.com/cmungall, https://github.com/mellybelly

depicted by

http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg

has related synonym

portion of cartilage tissue, cartilage, cartilages

id

UBERON:0002418

prefLabel

Cartilage tissue