roof plate
A single row of glia at the dorsal midline of the developing neural tube along the entire anterior-posterior axis. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. [ http://www.ncbi.nlm.nih.gov/pubmed/15378040 http://amigo.geneontology.org/amigo/term/GO:0021509 ]
Synonyms: roof plate neural tube, roofplate, roof plate neural tube region
Term info
- EMAPA:35361
- EHDAA:2891
- EHDAA2:0001270
- TAO:0001436
- EMAPA:16168
- ZFA:0001436
- TAO:0007058
- neuronames:1371
- EHDAA:916
- AAO:0011097
- ZFA:0007058
- VHOG:0000303
uberon_slim, pheno_slim, vertebrate_core
Multi-tissue structure that is the dorsal-most aspect of the devleloping neural tube.[TAO]
TODO - Note that although this is classically defined as being located on the neural tube, in many AOs the roof plate continues post-embryonically after the neural tube has ceased to exist. Consider 'roof plate of neural tube'. TODO - alar plate vs roof plate
alar plate, future brain roof plate
UBERON:0003298
uberon
UBERON:0003054
Term relations
- embryonic tissue
- ectoderm-derived structure
- cell layer
- composed primarily of some glial cell
- in dorsal side of some neural tube
- part of some neural tube