JSON

sclerotome

^ http://purl.obolibrary.org/obo/UBERON_0003089

Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. [ XB:curator http://en.wikipedia.org/wiki/Sclerotome https://github.com/obophenotype/uberon/issues/316 ]

Synonyms: sclerotomes

Term info

database cross reference
  • UMLS:C0183176 (ncithesaurus:Sclerotome)
  • FMA:295652
  • ZFA:0001080
  • AEO:0000212
  • TAO:0001080
  • XAO:0000397
  • EMAPA:31159
  • NCIT:C34287
  • Wikipedia:Sclerotome
  • VHOG:0000680
  • EHDAA2:0003439
  • AAO:0010571
Subsets

uberon_slim, pheno_slim, vertebrate_core

plural term
sclerotomes [ TAO:0001080 ]

UBPROP 0000001

Skeletogenic portion of somites.[AAO]

UBPROP 0000003

The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]

UBPROP 0000012

part_of somite in XAO

depicted by

http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png

has related synonym

sclerotomus

id

UBERON:0003089

imported from

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl

prefLabel

sclerotome