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optic fissure

^ http://purl.obolibrary.org/obo/UBERON_0005412

Groove that is in the developing ventral optic cup and through which blood vessels pass to the enclosed mesenchyme[ZFA]. a ventral fissure in the developing optic cup through which blood vessels pass to the enclosed mesenchyme[Free online medical dictionary]. [ http://medical-dictionary.thefreedictionary.com/optic+fissure https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3083162&group_id=36855 http://en.wikipedia.org/wiki/Choroid_fissure ZFA:0001284 ]

Synonyms: optic stalk fissure, choroid fissure - optic fissure, optic fissures

Term info

database cross reference
Subsets

pheno_slim, vertebrate_core

plural term
optic fissures [ ZFA:0001284 ]

UBPROP 0000001

A break in the continuity of the optic cup where the two sides of the cup meet.[AAO]

UBPROP 0000003

The folded arrangement of the vertebrate retina and RPE [retinal pigment epithelial] provides an evolutionary explanation for the occurrence of the choroid fissure, as proposed more than a century ago. Early in evolution, before the optic cup invaginated, the axons from retinal ganglion cells would simply have run over the surface of the structure. Hence, one can view the optic nerve as having acted rather like a rope in linking the retina to higher centres: the developing eye cup has simply wrapped around this 'rope', and the developing axons have thereby not needed to penetrate the retina.[well established][VHOG]

comment

Develeopment notes: As the eye starts to develop, a gap opens on the underside of each eye bud. This gap provides a way for the developing eye to be nourished. This gap, called the optic fissure, has to close before the eye is fully developed. Coloboma is the incomplete closer of the optic fissure

depicted by

http://upload.wikimedia.org/wikipedia/commons/9/98/Gray865.png

has related synonym

ventral choroidal fissure, choroid fissure

id

UBERON:0005412