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glomerular basement membrane

^ http://purl.obolibrary.org/obo/UBERON_0005777


The layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter. [ MP:0011348 http://www.informatics.jax.org/accession/anna ]

Synonyms: glomerular capillary basement membrane, glomerular filtration membrane

Term info

database cross reference
Subsets

pheno_slim, vertebrate_core

UBPROP 0000001

Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space.[TAO]

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png

id

UBERON:0005777

prefLabel

Glomerular basement membrane