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undifferentiated genital tubercle

^ http://purl.obolibrary.org/obo/UBERON_0005876

The embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin. [ MP:0011771 https://github.com/obophenotype/uberon/issues/1230 http://www.informatics.jax.org/accession/anna ]

Synonyms: undifferentiated genital tubercle

Term info

database cross reference
Subsets

pheno_slim

UBPROP 0000001

The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG], embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]

UBPROP 0000003

In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]

UBPROP 0000008

GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771], All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313], todo - add taxon constraints

UBPROP 0000012

we assume the EMAPA class is the undifferentiated form based on TS timings

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png

has related synonym

phallic tubercle, genital tubercle, tuberculum phallicum, tuberculum genitale

id

UBERON:0005876

prefLabel

undifferentiated genital tubercle