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germinal center

^ http://purl.obolibrary.org/obo/UBERON_0010754

A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. [ https://orcid.org/0000-0002-6601-2165 http://en.wikipedia.org/wiki/Germinal_center http://purl.obolibrary.org/obo/CL_tm ]

Synonyms: reaction center of follicle, central zone of follice

Term info

database cross reference
  • MESH:D018858
  • UMLS:C0282491 (ncithesaurus:Germinal_Center)
  • BTO:0003671
  • SCTID:64626006
  • Wikipedia:Germinal_center
  • NCIT:C13337
  • EV:0100051
comment

A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO]

depicted by

https://upload.wikimedia.org/wikipedia/commons/6/60/Germinal_center.svg

has related synonym

lymhpoid nodule, nodule

has narrow synonym

light zone of follicle

id

UBERON:0010754