JSON

Acne

^ http://purl.obolibrary.org/obo/HP_0001061

A skin condition in which there is an increase in sebum secretion by the pilosebaceous apparatus associated with open comedones (blackheads), closed comedones (whiteheads), and pustular nodules (papules, pustules, and cysts). [ HPO:probinson ]

Term info

database cross reference
  • MEDDRA:10000496 (Acne)
  • UMLS:C0702166
  • SNOMEDCT_US:11381005
Subsets

hposlim_core

comment

Acne can be a consequence of increased sebum production as a result of increased testosterone production (in males and females) during puberty. Blockage of hair follicles canresult from accumulating keratin and sebum, resulting in plug formation called microcomedone, which can enlarge just beneath the surface of the skin in the pore itself. It may become visible as a closed comedone (whitehead), a firm white papule. Further enlargement leads to an open comedone (blackhead). The comedones are not themselves inflammatory. Proprionibacterium acnes can induce inflammation, leding to an inflammed, red papule.

definition

A skin condition in which there is an increase in sebum secretion by the pilosebaceous apparatus associated with open comedones (blackheads), closed comedones (whiteheads), and pustular nodules (papules, pustules, and cysts).

has alternative id

HP:0005596

has broad synonym

Breaking out

id

HP:0001061

Term relations